<p style="color: #3c506c;" align="justify">Matrix metalloproteinases are a family of zinc and calcium dependent endopeptidases with the combined ability to degrade all the components of the extracellular matrix. MMP-3 (stromelysin-1), can degrade a broad range of substrates including collagen alpha &nbsp;chains, aggrecan, laminin, fibronectin, elastin, casein, alpha -1 antitrypsin, myelin basic protein, IL-1 beta, IGFBP-3, pro&nbsp;MMP-1, pro MMP-7, pro MMP-8, pro MMP-9 and pro&nbsp;MMP-13. The MMP-3 substrate repertoire extends beyond extracellular matrix proteins and implicates MMP-3 in roles other than direct tissue remodelling, for instance, enzyme cascades and cytokine regulation.</p> <p style="color: #3c506c;" align="justify">&nbsp;</p> <p style="color: #3c506c;" align="justify"><strong><span style="color: #f79646;"><span style="font-family: Helvetica Neue宋体;">性能参数</span></span></strong></p> <div class="tableResponsive" style="color: #3c506c;"> <table class="Table" style="width: 100%;" border="1" width="100%" cellspacing="1"> <tbody> <tr> <td valign="center"> <p align="justify"><strong>Synonyms</strong></p> </td> <td valign="center"> <p align="justify">Matrix Metalloproteinase-3, Stromelysin-1, SL-1, Transin-1</p> </td> </tr> <tr> <td valign="center"> <p align="justify"><strong>Uniprot No.</strong></p> </td> <td valign="center"> <p align="justify">P08254</p> </td> </tr> <tr> <td valign="center"> <p align="justify"><strong>Source</strong></p> </td> <td valign="center"> <p align="justify">Recombinant Human MMP-3 Protein&nbsp;is expressed from E.coli with His tag at the C-terminal. It contains Arg101-Cys477.</p> </td> </tr> <tr> <td valign="center"> <p align="justify"><strong>Molecular Weight</strong></p> </td> <td valign="center"> <p align="justify">Approximately&nbsp;&nbsp;42.8&nbsp;kDa.</p> </td> </tr> <tr> <td valign="center"> <p align="justify"><strong>Purity</strong></p> </td> <td valign="center"> <p align="justify">&gt; 95% as determined by SDS-PAGE.</p> </td> </tr> <tr> <td valign="center"> <p align="justify"><strong>Endotoxin</strong></p> </td> <td valign="center"> <p align="justify">&lt;1 EU per 1&mu;g of the protein by the LAL method.</p> </td> </tr> <tr> <td valign="center"> <p align="justify"><strong>Formulation</strong></p> </td> <td valign="center"> <p align="justify">Lyophilized from 0.22 &mu;m filtered solution in PBS (pH 7.4).</p> </td> </tr> <tr> <td valign="center"> <p align="justify"><strong>Reconstitution</strong></p> </td> <td valign="center"> <p align="justify">Centrifuge tubes before opening. The concentration of protein solution used for lyophilization is generally 1mg/mL. Dissolve lyophilized protein with sterile water to ensure the concentration is greater than 100 ug/mL.</p> </td> </tr> </tbody> </table> </div> <p style="color: #3c506c;" align="justify">&nbsp;</p> <p style="color: #3c506c;" align="justify"><strong><span style="color: #f79646;"><span style="font-family: Helvetica Neue宋体;">储存条件</span></span></strong></p> <p style="color: #3c506c;" align="justify">The product&nbsp;should&nbsp;be stored at -25~-15℃&nbsp;for 1 year from date of receipt.</p> <p style="color: #3c506c;" align="justify">2-7 days, 2 ~8 &deg;C under sterile conditions after reconstitution.</p> <p style="color: #3c506c;" align="justify">3 months, -25~-15℃ under sterile conditions after reconstitution.</p> <p style="color: #3c506c;" align="justify">Recommend to aliquot the protein into smaller quantities when first used&nbsp;and avoid repeated freeze-thaw cycles.</p> <p style="color: #3c506c;" align="justify">&nbsp;</p> <p style="color: #3c506c;" align="justify"><strong><span style="color: #f79646;"><span style="font-family: Helvetica Neue宋体;">注意事项</span></span></strong></p> <p style="color: #3c506c;" align="justify">1.Please operate with lab coats and disposable gloves,for your&nbsp;safety.</p> <p style="color: #3c506c;" align="justify">2.This product is for research use only.</p> <p style="color: #3c506c;" align="justify">&nbsp;</p> <p style="color: #3c506c;" align="justify"><strong><span style="color: #f79646;"><span style="font-family: Helvetica Neue宋体;">产品数据</span></span></strong></p> <p style="color: #3c506c;"><img src="https://upload.yeasen.com/file/56515/7ab6-168491254204731325.png" width="697" height="342" /></p> <p style="color: #3c506c;">Ver.&nbsp;CN20230411</p>